Asymptomatic ratio reaches 87.9%! New York Presbyterian Allen Hospital Maternal New Coronavirus Test

Asymptomatic ratio reaches 87.9%! New York Presbyterian Allen Hospital Maternal New Coronavirus Test
April 17, 2020 No Comments News

On April 13, 2020, Desmond Sutton of Columbia University Irvine Medical Center / New York Presbyterian Allen Hospital and others published in a CORRESPONDENCE published in the New England Journal of Medicine (NEJM) that the hospital treated 215 pregnant women The results of the new coronavirus PCR test showed that 15.3% of pregnant women were positive, and 87.9% of diagnosed patients did not show symptoms related to COVID-19.In recent weeks, COVID-19 has spread rapidly in New York City. During this pandemic, the obstetric population faced a unique challenge because these patients had multiple interactions with the healthcare system, and ultimately most patients were sent to hospital for delivery. Since Desmond Sutton and colleagues first diagnosed COVID-19 in a pregnant woman on March 13, 2020, they also shared the early experience of pregnant women with COVID-19, including the detection of two initially asymptomatic women after delivery Positive for SARS-CoV-2. After that, the hospital conducted a PCR test of nasopharyngeal swabs for pregnant women to check for infection.Between March 22 and April 4, 2020, a total of 215 pregnant women gave birth at Columbia University Irvine Medical Center / New York-Presbyterian Allen Hospital and Columbia University Irving Medical Center. All pregnant women were screened for COVID-19 symptoms upon admission. Four pregnant women (1.9%) developed fever or other symptoms of COVID-19 upon admission, and all 4 pregnant women tested positive for SARS-CoV-2 (Figure 1). None of the 211 asymptomatic women had a fever on admission. Of the 211 women without COVID-19 symptoms, 210 (99.5%) obtained nasopharyngeal swabs, of which 29 (13.7%) were positive for SARS-CoV-2. Of the 33 SARS-CoV-2 positive patients, 29 (87.9%) had no symptoms of COVID-19 on admission.
Figure 1.215 symptoms of obstetric delivery patients and SARS-CoV-2 test resultsAmong 29 asymptomatic women who were positive for SARS-CoV-2 at admission, 3 (10%) developed fever before discharge (median hospital stay, 2 days) after delivery. Two of the patients received antibiotics presumed to be endometritis (although one patient had no local symptoms), and one patient was assumed to have a fever due to COVID-19 and received supportive treatment. One patient had a negative nasopharyngeal swab at the time of admission, SARS-CoV-2 was negative, and had symptoms after delivery; the SARS-CoV-2 test was repeated 3 days after the initial test was positive.The center performed routine SARS-CoV-2 testing on all pregnant women who gave birth, and the results showed that during the New York pandemic, the single center ’s maternal SARS-CoV-2 was 15.3% (33/215) (29/33) SARS-CoV-2 positive pregnant women are asymptomatic patients. Of the 8 asymptomatic patients, more than 1 was seen in the delivery room. Although this prevalence rate is limited in geographic areas with low infection rates, it emphasizes the risk of COVID-19 in asymptomatic obstetric patients. In addition, because the SARS-CoV-2 test still has a certain proportion of false negative results, the true prevalence of infection may be underestimated.The author finally emphasizes that routine nucleic acid testing of pregnant women to determine their COVID-19 status can help hospitals adopt isolation measures and bed allocation, notify newborn care and guide personal protective equipment. In this challenging period, access to these clinical data provides an important opportunity to protect mothers, infants, and medical teams.

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